Bahney Musculoskeletal Regeneration Lab

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Orthopaedic Trauma Institute
2550 23rd Street, Building 9, 3rd Floor
San Francisco, CA, 94110
Tel: (628) 206-8812

The Laboratory for Musculoskeletal Regeneration is directed by Chelsea S. Bahney, PhD.


Our Work

Our research aims to develop novel therapies for the treatment of musculoskeletal diseases and injuries. Specifically, I believe we can drive improved tissue regeneration by recapitulating the normal sequences of development and repair. Current research projects in the laboratory focus on bone and cartilage regeneration.


In our laboratory we utilizes a cross-disciplinary tools based on expertise in biologically modified synthetic polymers, stem cell biology, and murine models of orthopaedic injuries. Chelsea completed a BS in Chemical Engineering from the University of Colorado, Boulder. Following her undergraduate degree she spent 5 years in Research & Development for industry working on working on radiofrequency based electrosurgical devices for tissue sealing (LigaSureTM). She then returned to complete a PhD in Cell & Developmental Biology from Oregon Health and Sciences University and a Post-Doctoral Fellowship at UCSF in pre-clinical models of bone regeneration. Projects in the laboratory are currently funded by the NIH, AO Foundation, Foundation of Orthopaedic Trauma (FOT), NSF Center for Disruptive Musculoskeletal Innovation, Orthopaedic Trauma Association (OTA), and UCSF Clinical and Translational Science Institute (CTSI) Catalyst Award.


A long-term research goal is to translate new biologics that change healthcare options in fracture healing and post-traumatic osteoarthritis.


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Orthopaedic Trauma Institute (OTI)

The Orthopaedic Trauma Institute (OTI) is a collaboration between the University of California, San Francisco (UCSF) and Zuckerberg San Francisco General (ZSFG). The OTI is the only trauma center in San Francisco specializing in the treatment and rehabilitation of musculoskeletal injuries. Regardless of where you live or which health insurance policy you carry, if you suffer a life- or limb-threatening injury in San Francisco, the ambulance will bring you to Zuckerberg San Francisco General Hospital and Trauma Center. Once there, you’ll find our team of UCSF Orthopaedic Department surgeons, specially trained to mend complex fractures all over the body.

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