Aaron Fields, PhD
Aaron Fields, PhD
Parnassus Heights - Fields Lab
513 Parnassus Ave
San Francisco CA 94143
415-502-3056
San Francisco CA 94143
Parnassus Heights
Publications
Awards and Honors
Grants
- Core Center for Musculoskeletal Biology and Medicine
2019-07-01 - 2024-06-30
NIH P30AR075055
Role: Co-Investigator
- UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
2019-09-25 - 2024-05-31
NIH U19AR076737
Role: Co-Investigator
- Role of the gut microbiome in the progression of vertebral endplate bone marrow lesions (Modic changes) in chronic low back pain
2021-05-01 - 2022-04-30
UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
Role: Principal Investigator
- Role of the cartilage endplate in spinal disc degeneration
2017-04-01 - 2022-01-31
NIH R01AR070198
Role: Principal Investigator
- Novel imaging of endplate biomarkers in chronic low back pain
2019-09-26 - 2021-08-31
NIH UH2AR076719
Role: Principal Investigator
- Enhancing cartilage endplate permeability to improve disc nutrition
2020-07-01 - 2021-06-30
UCSF School of Medicine
Role: Principal Investigator
- Phenotypes of pathologic vertebral endplate degeneration
2013-08-01 - 2020-08-31
NIH R56AR063705
Role: Co-Investigator
- Does enhancing cartilage endplate permeability improve nucleus pulposus cell function?
2019-01-01 - 2019-12-31
North American Spine Society
Role: Principal Investigator
- Does Cartilage Endplate Permeability Impact Nucleus Pulposus Cell Function?
2017-01-01 - 2017-12-31
North American Spine Society
Role: Principal Investigator
- Measurement of the effect of cartilage endplate permeability on disc cell function using in situ hybridization
2016-06-01 - 2017-05-31
UCSF Core Center for Musculoskeletal Biology in Medicine
Role: Principal Investigator
- Enhancing endplate permeability to treat or prevent intervertebral disc degeneration
2015-10-01 - 2016-09-30
UCSF Center for Disruptive Musculoskeletal Innovation
Role: Principal Investigator
- Cartilage endplate composition and disc degeneration: investigating nutrient diffusion and disc cell viability
2015-07-01 - 2016-06-30
UCSF School of Medicine
Role: Principal Investigator
- Endplate dysfunction and disc degeneration: investigating solute transport, disc cell viability and new imaging methods
2015-04-03 - 2016-06-30
UCSF Core Center for Musculoskeletal Biology in Medicine
Role: Principal Investigator
- Novel imaging of endplate biomarkers in chronic low back pain
2019-09-26 - 2024-08-31
NIH UH3AR076719
Role: Principal Investigator
- UCSF Musculoskeletal Training Program
2023-04-01 - 2028-03-31
NIH T32AR080618
Role: Program Director
Education
| University of California | 2019 | ||
| Postdoctoral Fellowship | University of California, San Francisco | 2013 | |
| PhD | University of California, Berkeley | 2010 | |
| BS | University of Denver | 2005 |
About Aaron Fields, PhD
Aaron Fields, Ph.D., is an Associate Professor of Orthopaedic Surgery at UCSF. He received his Bachelor of Science degree in Mechanical Engineering from the University of Denver in 2005, and his Masters and Doctoral degrees, also in Mechanical Engineering, from the University of California, Berkeley in 2008 and 2010. His undergraduate research was on the use of probabilistic techniques to evaluate knee implant performance, and both of his graduate thesis projects focused on discovering the mechanisms of vertebral fragility using high-resolution computational models. Aaron was appointed to a faculty position at UCSF after completing his post-doctoral fellowship in Orthopaedic Surgery in 2015. His background includes extensive research in experimental and computational biomechanics. Aaron is an active member of the Orthopaedic Research Society and the International Society for the Study of the Lumbar Spine.
Aaron currently directs the Orthopaedic Biomechanics and Biotransport Laboratory at UCSF. The lab's broad research interests are related to structure-function relationships in musculoskeletal tissues, with a particular focus on the mechanisms of nutrient transport in bone and cartilage and harnessing nutrient transport for tissue repair and regeneration. The lab combines engineering and biology approaches for (1) understanding the effects of aging and disease on structure-transport relationships and (2) developing translatable diagnostic and therapeutic strategies. An overall theme of this research is the use of advanced experimental and computational tools to measure how tissue constituents at the nano- and microscales impact whole-organ behavior.
Current projects:
1. diagnostic tools for assessing endplate permeability and therapies for enhancing endplate permeability
2. role of lacunar-canalicular system permeability in osteonecrosis of the femoral head
3. nanoscale and microscale contributions to diabetic skeletal fragility
