Faculty

Tamara Alliston, PhD

Tamara Alliston, PhD

Professor
Parnassus Heights - Alliston Lab
 
Parnassus Heights
 

Publications

Grants

  • The mechanistic control of bone quality and joint crosstalk by osteocytes
    2008-07-01 - 2025-05-31
    NIH R01DE019284
    Role: Principal Investigator
  • Core Center for Musculoskeletal Biology and Medicine (Overall Application)
    2019-07-01 - 2024-06-30
    NIH P30AR075055
    Role: Principal Investigator
  • miRNA coordination of TGF-beta / Wnt signaling in osteocyte mechanotransduction
    2017-08-01 - 2020-07-31
    NIH R21AR070403
    Role: Principal Investigator
  • 2018 Musculoskeletal Biology and Bioengineering Gordon Research Conference and Gordon Research Seminar
    2018-03-23 - 2019-02-28
    NIH R13AR073652
    Role: Principal Investigator
  • The mechanobiology of TGF-beta signaling in chondrocytes
    2014-09-18 - 2017-08-31
    NIH R21AR067439
    Role: Principal Investigator
  • AAOS/ORS Tackling Joint Disease by Understanding Crosstalk between Cartilage and Bone Research Symposium
    2015-09-21 - 2016-08-31
    NIH R13AR068913
    Role: Principal Investigator
  • TGF-Beta regulation of Runx2 in bone formation and quality
    2006-03-01 - 2009-02-28
    NIH R03DE016868
    Role: Principal Investigator

Education

PhD Baylor College of Medicine
B.A. Trinity University
Post-doc University of California San Francisco

About Tamara Alliston, PhD

Our research focuses on the mechanobiologic pathways controlling stem cell and skeletal cell differentiation in bone and cartilage. We seek to understand how these pathways maintain the mechanical integrity of the healthy skeleton, and how this is disrupted in skeletal diseases like arthritis and osteoporosis.

In particular, we study the mechanobiology of TGFβ in the skeleton. To answer these questions we combine molecular, cellular, physiologic, bioengineering, and materials science approaches. This interdisciplinary approach will advance the development of therapies that can prevent skeletal disease and improve the speed and success of skeletal tissue regeneration.

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