Jeffrey Lotz, PhD

Jeffrey Lotz, PhD

Jeffrey Lotz, PhD

Professor
Basic Science
Parnassus Heights - Lotz Lab

 

Education


PhD MIT/Harvard University 09/1988
MS Stanford University 06/1980
BS University of California 06/1979

Publications

Grants & Awards

  • UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
    September 25, 2019 - May 31, 2024
    NIH/NIAMS U19AR076737
    Role: Principal Investigator
  • Core Center for Musculoskeletal Biology and Medicine (Overall Application)
    July 1, 2019 - June 30, 2024
    NIH/NIAMS P30AR075055
    Role: Principal Investigator
  • Non-Thermal Pulsed FUS for Treatment of Intervertebral Disc Degeneration
    April 1, 2017 - January 31, 2019
    NIH/NIBIB R21EB024347
    Role: Co-Principal Investigator
  • Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    March 1, 2017 - February 29, 2020
    NIH/NIDCR U24DE026914
    Role: Principal Investigator
  • A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes
    September 1, 2016 - August 31, 2017
    NIH/NIAMS R41AR068202
    Role: Principal Investigator
  • University of California Tissue Regeneration Resource Center (UCTRRC)
    September 8, 2015 - August 31, 2016
    NIH/NIDCR R34DE025592
    Role: Principal Investigator
  • UCSF Core Center for Musculoskeletal Biology and Medicine
    July 1, 2014 - June 30, 2019
    NIH/NIAMS P30AR066262
    Role: Principal Investigator
  • Phenotypes of pathologic vertebral endplate degeneration
    August 1, 2013 - May 31, 2018
    NIH/NIAMS R01AR063705
    Role: Principal Investigator
  • Phenotypes of pathologic vertebral endplate degeneration
    August 1, 2013 - August 31, 2020
    NIH/NIAMS R56AR063705
    Role: Principal Investigator
  • Structured co-culture of stem cells and chondrocytes for spinal disc repair
    July 1, 2012 - April 30, 2014
    NIH/NIAMS R21AR063357
    Role: Principal Investigator
  • Endplate permeability and spinal disc degeneration
    July 1, 2007 - June 30, 2012
    NIH/NIAMS R01AR052811
    Role: Principal Investigator
  • Intervertebral disc repair with Mesenchymal Stem Cells
    August 20, 2005 - July 31, 2010
    NIH/NIAMS R01AR052712
    Role: Principal Investigator
  • Mesenchymal Stem Cell Differentiation &Mechanoplasticity
    July 22, 2004 - April 30, 2009
    NIH/NIAMS R01AR049786
    Role: Principal Investigator
  • Structure/function Relationships in Annulus Fibrosus
    April 1, 2004 - January 31, 2010
    NIH/NIAMS R01AR049770
    Role: Principal Investigator
  • ANALYSIS OF INJURY AVOIDANCE STRATEGIES DURING FALLS
    September 20, 2000 - August 31, 2004
    NIH/NIAMS R01AR046890
    Role: Principal Investigator
  • TOLERANCE OF THE INTERVERTEBRAL DISC
    September 30, 1998 - August 31, 2003
    NIH/NIAMS R01AR046173
    Role: Principal Investigator
  • INTERVERTEBRAL DISC INJURY MECHANISMS AND TOLERANCE
    May 1, 1998 - March 31, 2002
    NIH/NIAMS R01AR044179
    Role: Principal Investigator
  • UCSF/UCB Joint Graduate Group in BIoengineering
    July 1, 1985 - June 30, 2021
    NIH/NIGMS T32GM008155
    Role: Co-Principal Investigator
  • MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
    September 15, 1977 - December 31, 2003
    NIH/NIAMS P60AR020684
    Role: Co-Investigator

Membership & Committees

About Jeffrey Lotz, PhD

Jeffrey C. Lotz, PhD, holds the David S. Bradford, MD, Endowed Chair in Orthopaedic Surgery and vice chair for research. He has earned several awards for spine research, and serves as a deputy editor for the journal Spine. Dr. Lotz is the founding director of the UCSF Core Center for Musculoskeletal Biology in Medicine and the NSF Center for Disruptive Musculoskeletal Innovations, and corresponding PI for the newly-established Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR). He has expertise in spine biomechanics, intervertebral disc biology, and tissue engineering. His laboratory work focuses on identifying mechanisms of disc degeneration, developing novel diagnostics and therapies for low back pain, and the biomechanics of spinal instrumentation.

Awards Honors

  • Henry Farfan Award for outstanding contributions in spine related basic science research
    2018
    Henry Farfan Award for outstanding contributions in spine related basic science research, North American Spine Society, 2018
    North American Spine Society
  • Grammer/European Spine Journal Award
    2017
    Grammer/European Spine Journal Award, EuroSpine, 2017
    EuroSpine
  • ISSLS Prize for Low Back Pain Research
    2017
    ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2017
    International Society for the Study of the Lumbar Spine
  • Outstanding Paper Award
    2017
    Outstanding Paper Award, The Spine Journal and the North American Spine Society, 2017
    The Spine Journal and the North American Spine Society
  • Founding Board Member, Treasurer
    2015
    Founding Board Member, Treasurer, Orthopaedic Research Society Spine Section, 2015
    Orthopaedic Research Society Spine Section
  • Best Paper Award (co-author)
    2013
    Best Paper Award (co-author), International Society for the Study of the Lumbar Spine, 2013
    International Society for the Study of the Lumbar Spine
  • Best New Technology in Spine Care (co-inventor)
    2011
    Best New Technology in Spine Care (co-inventor), Orthopedics This Week, 2011
    Orthopedics This Week
  • Best Paper Award (co-author)
    2011
    Best Paper Award (co-author), Philadelphia Spine Research Society, 2011
    Philadelphia Spine Research Society
  • Fellow
    2008
    Fellow, American Institute for Medical and Biological Engineering, 2008
    American Institute for Medical and Biological Engineering
  • ISSLS Prize for Low Back Pain Research
    2007
    ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2007
    International Society for the Study of the Lumbar Spine
  • Deputy Editor
    2005 - 2017
    Deputy Editor, Spine, 2005-2017
    Spine
  • Medtronic Sofamor Danek Best Poster Award
    2001
    Medtronic Sofamor Danek Best Poster Award, International Society for the Study of the Lumbar Spine, 2001
    International Society for the Study of the Lumbar Spine
  • Norby-Smith Award for Minimally Invasive Surgery
    2000
    Norby-Smith Award for Minimally Invasive Surgery, Spine Arthroplasty Society, 2000
    Spine Arthroplasty Society
  • Panelist for Musculoskeletal Disorders and the Workplace
    1999
    Panelist for Musculoskeletal Disorders and the Workplace, National Research Council, 1999
    National Research Council
  • Volvo Award for Low Back Pain Research
    1998
    Volvo Award for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 1998
    International Society for the Study of the Lumbar Spine
  • AcroMed Award for Outstanding Spinal Research
    1993
    AcroMed Award for Outstanding Spinal Research, North American Spine Society, 1993
    North American Spine Society

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