UCSF Department of Orthopaedic Surgery

UCSF Core Center for Patient-centric Mechanistic Phenotyping in Chronic Low Back Pain
September 25, 2019 - May 31, 2024
NIH/NIAMS U19AR076737
Role: Principal Investigator

Core Center for Musculoskeletal Biology and Medicine (Overall Application)
July 1, 2019 - June 30, 2024
NIH/NIAMS P30AR075055
Role: Principal Investigator

Non-Thermal Pulsed FUS for Treatment of Intervertebral Disc Degeneration
April 1, 2017 - January 31, 2019
NIH/NIBIB R21EB024347
Role: Co-Principal Investigator

Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
March 1, 2017 - February 29, 2020
NIH/NIDCR U24DE026914
Role: Principal Investigator

A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes
September 1, 2016 - August 31, 2017
NIH/NIAMS R41AR068202
Role: Principal Investigator

University of California Tissue Regeneration Resource Center (UCTRRC)
September 8, 2015 - August 31, 2016
NIH/NIDCR R34DE025592
Role: Principal Investigator

UCSF Core Center for Musculoskeletal Biology and Medicine
July 1, 2014 - June 30, 2019
NIH/NIAMS P30AR066262
Role: Principal Investigator

Phenotypes of pathologic vertebral endplate degeneration
August 1, 2013 - May 31, 2018
NIH/NIAMS R01AR063705
Role: Principal Investigator

Phenotypes of pathologic vertebral endplate degeneration
August 1, 2013 - August 31, 2020
NIH/NIAMS R56AR063705
Role: Principal Investigator

Structured co-culture of stem cells and chondrocytes for spinal disc repair
July 1, 2012 - April 30, 2014
NIH/NIAMS R21AR063357
Role: Principal Investigator

Endplate permeability and spinal disc degeneration
July 1, 2007 - June 30, 2012
NIH/NIAMS R01AR052811
Role: Principal Investigator

Intervertebral disc repair with Mesenchymal Stem Cells
August 20, 2005 - July 31, 2010
NIH/NIAMS R01AR052712
Role: Principal Investigator

Mesenchymal Stem Cell Differentiation &Mechanoplasticity
July 22, 2004 - April 30, 2009
NIH/NIAMS R01AR049786
Role: Principal Investigator

Structure/function Relationships in Annulus Fibrosus
April 1, 2004 - January 31, 2010
NIH/NIAMS R01AR049770
Role: Principal Investigator

ANALYSIS OF INJURY AVOIDANCE STRATEGIES DURING FALLS
September 20, 2000 - August 31, 2004
NIH/NIAMS R01AR046890
Role: Principal Investigator

TOLERANCE OF THE INTERVERTEBRAL DISC
September 30, 1998 - August 31, 2003
NIH/NIAMS R01AR046173
Role: Principal Investigator

INTERVERTEBRAL DISC INJURY MECHANISMS AND TOLERANCE
May 1, 1998 - March 31, 2002
NIH/NIAMS R01AR044179
Role: Principal Investigator

UCSF/UCB Joint Graduate Group in BIoengineering
July 1, 1985 - June 30, 2021
NIH/NIGMS T32GM008155
Role: Co-Principal Investigator

MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR
September 15, 1977 - December 31, 2003
NIH/NIAMS P60AR020684
Role: Co-Investigator

Membership & Committees

About Jeffrey Lotz, PhD

Jeffrey C. Lotz, PhD, holds the David S. Bradford, MD, Endowed Chair in Orthopaedic Surgery and vice chair for research. He has earned several awards for spine research, and serves as a deputy editor for the journal Spine. Dr. Lotz is the founding director of the UCSF Core Center for Musculoskeletal Biology in Medicine and the NSF Center for Disruptive Musculoskeletal Innovations, and corresponding PI for the newly-established Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR). He has expertise in spine biomechanics, intervertebral disc biology, and tissue engineering. His laboratory work focuses on identifying mechanisms of disc degeneration, developing novel diagnostics and therapies for low back pain, and the biomechanics of spinal instrumentation.

Awards Honors

Henry Farfan Award for outstanding contributions in spine related basic science research
2018
Henry Farfan Award for outstanding contributions in spine related basic science research, North American Spine Society, 2018
North American Spine Society

Grammer/European Spine Journal Award
2017
Grammer/European Spine Journal Award, EuroSpine, 2017
EuroSpine

ISSLS Prize for Low Back Pain Research
2017
ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2017
International Society for the Study of the Lumbar Spine

Outstanding Paper Award
2017
Outstanding Paper Award, The Spine Journal and the North American Spine Society, 2017
The Spine Journal and the North American Spine Society

Founding Board Member, Treasurer
2015
Founding Board Member, Treasurer, Orthopaedic Research Society Spine Section, 2015
Orthopaedic Research Society Spine Section

Best Paper Award (co-author)
2013
Best Paper Award (co-author), International Society for the Study of the Lumbar Spine, 2013
International Society for the Study of the Lumbar Spine

Best New Technology in Spine Care (co-inventor)
2011
Best New Technology in Spine Care (co-inventor), Orthopedics This Week, 2011
Orthopedics This Week

Best Paper Award (co-author)
2011
Best Paper Award (co-author), Philadelphia Spine Research Society, 2011
Philadelphia Spine Research Society

Fellow
2008
Fellow, American Institute for Medical and Biological Engineering, 2008
American Institute for Medical and Biological Engineering

ISSLS Prize for Low Back Pain Research
2007
ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2007
International Society for the Study of the Lumbar Spine

Deputy Editor
2005 - 2017
Deputy Editor, Spine, 2005-2017
Spine

Medtronic Sofamor Danek Best Poster Award
2001
Medtronic Sofamor Danek Best Poster Award, International Society for the Study of the Lumbar Spine, 2001
International Society for the Study of the Lumbar Spine

Norby-Smith Award for Minimally Invasive Surgery
2000
Norby-Smith Award for Minimally Invasive Surgery, Spine Arthroplasty Society, 2000
Spine Arthroplasty Society

Panelist for Musculoskeletal Disorders and the Workplace
1999
Panelist for Musculoskeletal Disorders and the Workplace, National Research Council, 1999
National Research Council

Volvo Award for Low Back Pain Research
1998
Volvo Award for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 1998
International Society for the Study of the Lumbar Spine

AcroMed Award for Outstanding Spinal Research
1993
AcroMed Award for Outstanding Spinal Research, North American Spine Society, 1993
North American Spine Society