Jeffrey Lotz, PhD
Jeffrey Lotz, PhD
Professor
Basic Science
Education
| PhD | MIT/Harvard University | 09/1988 | |
| MS | Stanford University | 06/1980 | |
| BS | University of California | 06/1979 |
Publications
- Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC. Pathobiology of Modic changes. Eur Spine J. 2016 Feb 25. PMID: 26914098
- Lotz JC, Fields AJ, Liebenberg EC. The role of the vertebral end plate in low back pain. Global Spine J. 2013 Jun; 3(3):153-64. PMID: 24436866
- Lotz JC. Load and the spine. How does the Goldilocks principle apply? Spine J. 2011 Jan; 11(1):44-5. PMID: 21168097
- Lotz JC. Trials of vertebroplasty for vertebral fractures. N Engl J Med. 2009 Nov 19; 361(21):2098; author reply 2099-100. PMID: 19938315
- Schultz DS, Rodriguez AG, Hansma PK, Lotz JC. Mechanical profiling of intervertebral discs. J Biomech. 2009 May 29; 42(8):1154-7. PMID: 19345361
- Lotz JC, Kim AJ. Disc regeneration: why, when, and how. Neurosurg Clin N Am. 2005 Oct; 16(4):657-63, vii. PMID: 16326289
- Lotz JC. Animal models of intervertebral disc degeneration: lessons learned. Spine (Phila Pa 1976). 2004 Dec 1; 29(23):2742-50. PMID: 15564923
- Rousseau MA, Bass EC, Lotz JC. Ventral approach to the lumbar spine of the Sprague-Dawley rat. Lab Anim (NY). 2004 Jun; 33(6):43-5. PMID: 15179439
- Walsh AJ, Lotz JC. Biological response of the intervertebral disc to dynamic loading. J Biomech. 2004 Mar; 37(3):329-37. PMID: 14757452
- Whyne CM, Hu SS, Workman KL, Lotz JC. Biphasic material properties of lytic bone metastases. Ann Biomed Eng. 2000 Sep; 28(9):1154-8. PMID: 11132199
- Lotz J, Gaertner T, Hahn M, Prellwitz W. Collagen type I metabolism after bone surgery. Arch Orthop Trauma Surg. 1999; 119(3-4):212-6. PMID: 10392522
Grants & Awards
- 2021, UCSF/UCB Joint Graduate Group in BIoengineering, T32GM008155
- 2019, UCSF Core Center for Musculoskeletal Biology and Medicine, P30AR066262
- 2018, Phenotypes of pathologic vertebral endplate degeneration, R01AR063705
- 2017, A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes, R41AR068202
- 2016, University of California Tissue Regeneration Resource Center (UCTRRC), R34DE025592
- 2014, Structured co-culture of stem cells and chondrocytes for spinal disc repair, R21AR063357
- 2012, Endplate permeability and spinal disc degeneration, R01AR052811
- 2010, Intervertebral disc repair with Mesenchymal Stem Cells, R01AR052712
- 2010, Structure/function Relationships in Annulus Fibrosus, R01AR049770
- 2009, Mesenchymal Stem Cell Differentiation &Mechanoplasticity, R01AR049786
- 2004, ANALYSIS OF INJURY AVOIDANCE STRATEGIES DURING FALLS, R01AR046890
- 2003, TOLERANCE OF THE INTERVERTEBRAL DISC, R01AR046173
- 2003, MULTIPURPOSE ARTHRITIS AND MUSCULOSKELETAL DISEASES CTR, P60AR020684
- 2002, INTERVERTEBRAL DISC INJURY MECHANISMS AND TOLERANCE, R01AR044179
Membership & Committees
About Jeffrey Lotz, PhD
Jeffrey C. Lotz, PhD, holds the David S. Bradford, MD, Endowed Chair in Orthopaedic Surgery and vice chair for research. He has earned several awards for spine research, and serves as a deputy editor for the journal Spine. Dr. Lotz is the founding director of the UCSF Core Center for Musculoskeletal Biology in Medicine and the NSF Center for Disruptive Musculoskeletal Innovations, and corresponding PI for the newly-established Center for Dental, Oral and Craniofacial Tissue and Organ Regeneration (C-DOCTOR). He has expertise in spine biomechanics, intervertebral disc biology, and tissue engineering. His laboratory work focuses on identifying mechanisms of disc degeneration, developing novel diagnostics and therapies for low back pain, and the biomechanics of spinal instrumentation.
Awards Honors
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Outstanding Paper Award
2017
Outstanding Paper Award, The Spine Journal and the North American Spine Society, 2017
The Spine Journal and the North American Spine Society
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ISSLS Prize for Low Back Pain Research
2017
ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2017
International Society for the Study of the Lumbar Spine
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Grammer/European Spine Journal Award
2017
Grammer/European Spine Journal Award, EuroSpine, 2017
EuroSpine
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Founding Board Member, Treasurer
2015
Founding Board Member, Treasurer, Orthopaedic Research Society Spine Section, 2015
Orthopaedic Research Society Spine Section
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Best Paper Award (co-author)
2013
Best Paper Award (co-author), International Society for the Study of the Lumbar Spine, 2013
International Society for the Study of the Lumbar Spine
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Best Paper Award (co-author)
2011
Best Paper Award (co-author), Philadelphia Spine Research Society, 2011
Philadelphia Spine Research Society
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Best New Technology in Spine Care (co-inventor)
2011
Best New Technology in Spine Care (co-inventor), Orthopedics This Week, 2011
Orthopedics This Week
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Fellow
2008
Fellow, American Institute for Medical and Biological Engineering, 2008
American Institute for Medical and Biological Engineering
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ISSLS Prize for Low Back Pain Research
2007
ISSLS Prize for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 2007
International Society for the Study of the Lumbar Spine
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Deputy Editor
2005 - 2017
Deputy Editor, Spine, 2005-2017
Spine
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Medtronic Sofamor Danek Best Poster Award
2001
Medtronic Sofamor Danek Best Poster Award, International Society for the Study of the Lumbar Spine, 2001
International Society for the Study of the Lumbar Spine
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Norby-Smith Award for Minimally Invasive Surgery
2000
Norby-Smith Award for Minimally Invasive Surgery, Spine Arthroplasty Society, 2000
Spine Arthroplasty Society
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Panelist for Musculoskeletal Disorders and the Workplace
1999
Panelist for Musculoskeletal Disorders and the Workplace, National Research Council, 1999
National Research Council
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Volvo Award for Low Back Pain Research
1998
Volvo Award for Low Back Pain Research, International Society for the Study of the Lumbar Spine, 1998
International Society for the Study of the Lumbar Spine
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AcroMed Award for Outstanding Spinal Research
1993
AcroMed Award for Outstanding Spinal Research, North American Spine Society, 1993
North American Spine Society
