Xuhui Liu, MD

Xuhui Liu, MD

Professor
Feeley-Liu Lab for Muscle Regeneration - Basic/Translational Research
 

Publications

Awards and Honors

  • Kappa Delta Elizabeth Winston Lanier Award (Co-awardee)
    2025
    Kappa Delta Elizabeth Winston Lanier Award (Co-awardee), American Academy of Orthopaedic Surgeons, 2025
    American Academy of Orthopaedic Surgeons
  • Excellence in Research Award
    2021
    Excellence in Research Award, American Orthopaedic Society for Sports Medicine (AOSSM), 2021
    American Orthopaedic Society for Sports Medicine (AOSSM)
  • Charles S. Neer Award in Basic Science
    2020
    Charles S. Neer Award in Basic Science, American Shoulder and Elbow Surgeons, 2020
    American Shoulder and Elbow Surgeons
  • Kappa Delta Young Investigator Award (Co-awardee)
    2014
    Kappa Delta Young Investigator Award (Co-awardee), American Academy of Orthopaedic Surgeons, 2014
    American Academy of Orthopaedic Surgeons
  • Travel Award, Arthritis Research Conference, Stone Mountain, GA
    2005
    Travel Award, Arthritis Research Conference, Stone Mountain, GA, Arthritis Foundation, 2005
    Arthritis Foundation
  • Travel Award, Arthritis Research Conference, Keystone, CO
    2003
    Travel Award, Arthritis Research Conference, Keystone, CO, Arthritis Foundation, 2003
    Arthritis Foundation

Grants

  • Mitochondrial biogenesis and transfer to promote muscle regeneration
    2023-10-01 - 2027-09-30
    VA-ORO BLR&D 1 I01 BX006098-01
    Role: Co-investigator
  • Endogenous Stem Cells Promote Regeneration of Muscle in Rotator Cuff Repair
    2022-01-01 - 2026-12-31
    VA-ORO CSR&D I01 CX002200-01A2
    Role: Co-Investigator
  • Mirabegron in Treating Muscle Dystrophy
    2022-09-01 - 2025-08-31
    Muscular Dystrophy Association MDA 957140
    Role: PI
  • Matrix-Assisted Cell Transplantation of Promyogenic Fibroadipogenic Progenitor (FAP) Stem Cells
    2022-04-01 - 2024-09-30
    California Institute of Regenerative Medicine DISC2-13201
    Role: Co-investigator
  • Utilizing beige fat to improve muscle function after rotator cuff repair
    2018-09-01 - 2023-06-30
    NIH R01AR072669
    Role: Co-Investigator
  • The role of P16Ink4a in adult skeletal muscle stem cells
    2021-08-17 - 2026-05-31
    NIH R01AR079244
    Role: Co-Investigator
  • Fibro/adipogenic progenitor (FAP) in neuro-muscular junction health with ALS
    2024-07-01 - 2025-06-30
    UCSF RAP
    Role: PI
  • Niche Regulation of Muscle Stem Cells
    2019-08-01 - 2024-05-31
    NIH R01AR076252
    Role: PI

Education

Postdoc Baylor College of Medicine 01/2006
MD Peking Union Medical College 07/2001

About Xuhui Liu, MD

Xuhui Liu, M.D. was trained as a physician and a research scientist in the field of orthopedic surgery. He graduated from Peking Union Medical College in 2021 and received extensive research training as a postdoc at Baylor College of Medicine before he joined UCSF. In the past fifteen years, his research has been focused on translational biomedical researches that lead to new treatments to benefit orthopedic patients. His main research interests include stem cells and key molecular pathways that are involved in skeletal muscle atrophy, fibrosis and fat infiltration. Specifically, Dr. Liu's research focused on a muscle stem cell populations, including satellite cells (SCs) and fibro/adipogenic progenitors (FAPs) in various muscle disorders. We discovered a novel brown/beige fat (BAT) differentiation of FAP in both mouse and human muscles. Inducing FAP BAT differentiation with beta adrenergic receptor agonists improves muscle regeneration after direct and indirect injuries. His most recent research involves in FAP in Duchenne muscular dystrophy (DMD) and ALS. His lab research is committed to discover novel mechanisms of muscle regeneration thus to develop new treatments to improve muscle function and the quality of life of the patients.