Xuhui Liu, MD

Xuhui Liu, MD

Xuhui Liu, MD

Professor

Basic Science

Feeley-Liu Lab for Muscle Regeneration - Basic Science

1700 Owens Street, Room 364
San Francisco CA 94158

415-575-0546
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Publications

J.H. Jay, M. Liu, X. Liu, B.T. Feeley, C.S. Sabatini. Does the Antimalarial Drug Quinine Contribute to Muscle Fibro/Adipogenic Progenitor Fibrogenesis?. Muscles Ligaments and Tendons Journal. 2021 Nov 1; 11(04):635. PMID:

Michael R. Davies, Gurbani Kaur, Xuhui Liu, Francisco Gomez Alvarado, Prashant Nuthalapati, Mengyao Liu, Agustin Diaz, Jeffrey C. Lotz, Jeannie F. Bailey, Brian T. Feeley. Paraspinal Muscle Degeneration and Regenerative Potential in a Murine Model of Lumbar Disc Injury. North American Spine Society Journal (NASSJ). 2021 Jun 1; 6:100061. PMID:

G. Kaur, M.R. Davies, X. Liu, B.T. Delioglu. The Role of Fibro-Adipogenic Progenitors in Musculoskeletal Disease. Muscles Ligaments and Tendons Journal. 2021 May 1; 11(02):201. PMID:

M. Liu, Z. Wang, C.S. Lee, C. Nguyen, L. Lee, H.T. Kim, B.T. Feeley, X. Liu. Brown Beige Fat Activation after Skeletal Muscle Ischemia-Reperfusion Injury. Muscles Ligaments and Tendons Journal. 2020 Nov 1; 10(04):579. PMID:

Xuhui Liu, Mengyao Liu, Russell Turner, Urszula Iwaniec, Hubert Kim, Bernard Halloran. Dried plum mitigates spinal cord injury-induced bone loss in mice. JOR Spine. 2020 Jul 15. PMID:

Carlin Lee, Meng Yao Liu, C. Benjamin Ma, Xuhui Liu, Brian Feeley. Inducible endogenous stem cells within human rotator cuff muscle to promote muscle regeneration after rotator cuff repair. Orthopaedic Journal of Sports Medicine. 2020 Jul 1; 8(7_suppl6):2325967120s00332. PMID:

Obiajulu Agha, Andreas Mueller-Immergluck, Mengyao Liu, He Zhang, Alekos A. Theologis, Aaron Clark, Hubert T. Kim, Xuhui Liu, Brian T. Feeley, Jeannie F. Bailey. Intervertebral disc herniation effects on multifidus muscle composition and resident stem cell populations. JOR Spine. 2020 May 1. PMID:

Carlin Lee, Mengyao Liu, Obiajulu Agha, Hubert T. Kim, Xuhui Liu, Brian T. Feeley. Beige Fibro-Adipogenic Progenitors Reduce Muscle Degeneration in a Mouse Model of Delayed Repair for Massive Rotator Cuff Tears. Journal of Shoulder and Elbow Surgery. 2020 Apr 1; 29(4):e153-e155. PMID:

X. Liu, S. Joshi, B. Ravishankar, D. Laron, H.T. Kim, B.T. Feeley. Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 05(02):113. PMID:

X. Liu, A.Y. Ning, N. Chen Chang, H. Kim, R. Nissenson, L. Wang, B.T. Feeley. Investigating the cellular origin of rotator cuff muscle fatty infiltration and fibrosis after injury. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 06(01):6. PMID:

X. Liu, B. Ravishankar, A. Ning, M. Liu, H.T. Kim, B.T. Feeley. Knocking-out matrix metalloproteinase-13 exacerbates rotator cuff muscle fatty infiltration. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 07(02):202. PMID:

T Luan, X. Liu, J.T. Easley, B. Ravishankar, C. Puttlitz, B.T. Feeley. Muscle atrophy and fatty infiltration after an acute rotator cuff repair in a sheep model. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 05(02):106. PMID:

Q. Zhang, S.K. Joshi, D.H. Lovett, G. Manzano, H.T. Kim, X. Liu. Muscle extracellular matrix degradation and contractibility following tendon rupture and disuse. Muscles Ligaments and Tendons Journal. 2019 Jan 1; 03(01):35. PMID:

Brian Feeley, Xuhui Liu, Givenchy Manzano, Hubert Kim. Paper # 264: Evaluation of Mechanotransduction Pathways in the Development of Muscle Atrophy in a Small Animal Model of Massive Rotator Cuff Tears. Arthroscopy The Journal of Arthroscopic and Related Surgery. 2011 Oct 1; 27(10):e248-e249. PMID:

Xuhui Liu, Steven Garcia, Hubert Kim, Robert Raffai, Brian Feeley, Michael Davies. Poster 155: Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes that Treat Rotator Cuff Muscle Degeneration in Mice and are Identified in Humans by Single-Cell RNA Sequencing. Orthopaedic Journal of Sports Medicine. 2022 Jul 1; 10(7_suppl5):2325967121s00716. PMID:

About Xuhui Liu, MD

Xuhui Liu, MD is a research scientist in the field of orthopedic surgery. He obtained his MD degree from Peking Union Medical College in China in 2001. After that, he moved to USA and received his postdoctoral research training in Orthopedic Biochemistry and Biomechanics in Baylor College of Medicine in Houston, Texas. Dr. Liu joined the Department of Orthopedic Surgery at UCSF in 2006 as a Research Biologist. He was promoted to Assistant Professor in 2008 and Associate Professor in 2015. Majority of his research focuses on the molecular and cellular mechanism of degenerative musculoskeletal diseases. The cellular and molecular mechanism of muscle atrophy and fatty degeneration is within his central research interests. He is also interested in the role of central and peripheral nerve system in regulating musculoskeletal pathophysiology. His work has been supported by NIH, VA and private charities.