Ralph Marcucio, PhD
Ralph Marcucio, PhD
Orthopaedic Trauma Institute - Marcucio Lab
2550 23rd Street
San Francisco CA 94110
628-206-8812
San Francisco CA 94110
Orthopaedic Trauma Institute at Zuckerberg San Francisco General - Trauma & Problem Fractures
Publications
Grants
- Transcriptional regulatory landscapes underlying FEZ Formation
2020-03-11 - 2025-02-28
NIH R01DE028324
Role: Principal Investigator
- A Predictive Developmental Morphospace Model of Cleft Lip
2020-09-03 - 2021-08-31
NIH R56DE029124
Role: Co-Principal Investigator
- Understanding the Forces that Shape the Face
2018-09-15 - 2021-08-31
NIH R21DE028198
Role: Principal Investigator
- Molecular Basis of Tissue Interactions that Regulate Craniofacial Development
2007-06-01 - 2018-06-30
NIH R01DE018234
Role: Principal Investigator
- Effects of Aging on Macrophages and Bone Regeneration
2013-09-30 - 2018-05-31
NIH R01AG046282
Role: Principal Investigator
- Developmental mechanisms underlying genotype-phenotype correlations
2011-04-27 - 2017-03-31
NIH R01DE021708
Role: Principal Investigator
- BMP-Mediated Tissue Interactions that Pattern the Face
2005-01-01 - 2007-12-31
NIH R03DE015901
Role: Principal Investigator
- CELL DEATH IN EMBRYONIC HEAD MUSCLES
1996-09-01 - 1900-01-01
NIH F32DE005683
Role: Principal Investigator
- Cell Transitions during Bone Fracture Healing
2023-09-18 - 2028-08-31
NIH R01AR081671
Role: Principal Investigator
- The role of continuous phenotypic variation in structural defects of the face
2010-07-23 - 2026-11-30
NIH R01DE019638
Role: Principal Investigator
About Ralph Marcucio, PhD
Ralph Marcucio was born in and grew up in Amsterdam, N.Y. Dr. Marcucio began his research career as an intern at The Boyce Thompson Institute while he was an undergraduate at Cornell University in Ithaca, NY. After receiving his bachelor’s degree from Cornell University in 1990, Dr. Marcucio was accepted into Cornell University's School of Agriculture PhD program. He completed his PhD in 1995. For his exemplary performance and dedication as a Graduate Teaching Assistant, Dr. Marcucio was recognized by the Dean of Cornell University's School of Agriculture for his outstanding contribution to undergraduate education. After receiving his PhD, Ralph was awarded a prestigious NIH training grant to study tissue interactions that control development of the musculoskeletal system. Dr. Marcucio spent 5 years in the New York State College of Veterinary Medicine studying the origins of the musculature responsible for moving the head and jaw skeleton.
In 2000, Dr. Marcucio joined the Molecular and Cellular Biology Laboratory at the University of California, San Francisco, (UCSF). In this position, he began studying how the skeleton of the face attains its shape and form. This work has resulted in the preparation of numerous manuscripts for publication in world-renowned research journals and has formed the basis for his independent research career.
In 2003, Dr. Marcucio was appointed to the faculty at UCSF as an Assistant Professor in Residence in the Department of Orthopaedic Surgery. His research program focuses on two basic science areas. First, he studies bone fracture healing focusing on the transformation of chondrocytes to osteoblasts and other cell types, as well as the inflammatory process during healing. Second, Dr. Marcucio is examining the role that the brain plays during normal development of the facial skeleton. Many facial birth defects have an underlying brain malformation, and the goal of the research is to generate novel therapeutic approaches that will allow correcting facial malformations prior to birth.
Dr. Marcucio is a dedicated and enthusiastic mentor to dental and medical students. His students have been invited to participate in university, state, national, and international research competitions.
Visit: Marcucio Molecular and Cellular Biology Lab
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