• Consortium of Orthopaedic Academic Traumatologists

  • PREP-IT Research Team

  • Center for Evidence-Based Orthopaedics

McMaster University
Department of Orthopaedic Surgery

293 Wellington St. North, Suite 110
Hamilton, ON, L8L 8E7
Email: silviali@mcmaster.ca

Our mission

To educate and empower the surgeons of tomorrow with the capacity for evidence-based clinical care, critical thinking, creativity, professionalism, and a proclivity towards lifelong learning.

Our team

  • Dr. Mohit Bhandari

    • Principle Investigator, McMaster University

  • Dr. PJ Devereaux

    • Principle Investigator, McMaster University

  • Dr. Rebecca Ivers

    • George Institute for Global Health, Australia

Our work

  • In alignment with the World Health Organization's objectives for the "Decade of Action for Road Safety", there is a dire need for a large prospective cohort study to identify potentially modifiable risk factors associated with major adverse outcomes in patients with musculoskeletal injuries.

Our projects

International Orthopaedic Multicenter Study in Fracture Care (INORMUS)

  • INORMUS aims to determine, among adult individuals who present to hospital with musculoskeletal trauma, the following: 1) mechanisms of injury and details of early treatment and transport to hospital; 2) the incidence of major complications (mortality, re-operation, and infection) within 30 days post-hospital admission; and 3) modifiable patient, system, and treatment factors associated with these major complications.

PREPARE (PREP-IT Program)

  • PREPARE is a cluster randomized crossover trial of at least 7,820 patients with open and closed fractures comparing the effectiveness of two antiseptic skin preparation solutions, iodine-povacrylex (0.7% free iodine) in alcohol versus 2% chlorhexidine gluconate. The primary outcome is surgical site infection and secondary outcomes are unplanned fracture-related reoperation and health-related quality of life..

Aqueous-PREP

  • Aqueous-PREP is a cluster randomized crossover trial of at least 1,540 patients with open fractures comparing the effectiveness of two aqueous antiseptic skin preparation solutions, 10% povidone-iodine (1% free iodine) and 4% chlorhexidine gluconate. The primary outcome is surgical site infection and secondary outcome is unplanned fracture-related reoperation.

General link

Website: https://surgery.mcmaster.ca/divisions/orthopaedic-surgery

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